6 top peptide skincare products for youthful skin & fine lines

If there’s one thing sure in life, it’s that we can’t stop the passing of time. However, with advantages in beauty technology, dozens of products on the market claim to be able to ‘reverse’ the signs of aging – or at the very least, prevent it.

But how do you determine which skincare products are effective in antiaging when there are so many active ingredients, buzzwords and technical terms to navigate?

Sometimes it can feel like you need a science degree to understand what you’re putting on your face, but we hope to tackle that as we introduce you to one of the most effective antiaging agents to look out for on the back of your bottles.

Peptides are one of the most talked-about ingredients in the field of antiaging skincare and any skin type can benefit from them.

They are found naturally in the skin, but after age 30, natural production starts to drop considerably, so skin sometimes needs a helping hand in the form of products.

This skincare guide will give you the lowdown on what they are, and their benefits, debunk myths and recommend some favorite peptide-powered skincare products you can buy, starting from as little as $16 [1].

Here is your ultimate guide to peptides.

We’ve spoken to the Paula’s Choice UK Education Team and here is why you should incorporate more peptides into your skincare routine [2].

What are peptides and where do they come from?

Collagen, elastin and keratin are built from peptides, which are short chains of amino acids. It is these proteins that give your skin its texture, strength, and resilience.

Peptides are naturally present in the human body but can also be applied through skincare to strengthen the skin’s natural proteins. The ones used in skincare are synthetically made to perform particular tasks.

What benefits do they have in skincare?

Research shows they can smooth wrinkles, smooth irritated skin, restore elasticity, strengthen the barrier, increase hydration and firm the skin. But peptides do not possess magical properties, as some brands claim.

No single ingredient will address all signs of skin aging. While it’s clear that peptides are unique, they are not enough to transform your skin as an isolated ingredient.

This means every skincare product should also contain other effective ingredients, such as antioxidants and skin-repairing.

What benefits do they have in skincare?

How can peptides be integrated to a skincare routine?

A moisturizer, SPF and eye cream containing peptides is an excellent first choice for slow-aging benefits.

Targeted boosters or treatments with peptides are more effective for addressing advanced skin concerns, such as fine lines, loss of firmness, and wrinkles.

So, if you’re looking for a new peptide product to trial, which one should you choose? Here are some top recommendations:

Paula’s Choice

Recently launched, the new Pro-Collagen Multi-Peptide Booster (starts at $19) harnesses newly researched peptide technology [3].

The cutting-edge serum goes beyond the surface level of the skin to rebuild and lift the skin’s deeper dermal-epidermal junction. 

Hydrating hyaluronic acid and strengthening amino acids simultaneously plump the skin and maintain overall health.

The Power Peptide Complex not only delivers visible results within 15 minutes but results that last up to four weeks [4].

Over time users can expect to see dramatically diminished appearance of wrinkle depth and volume for a remarkably younger appearance overall, reduced crow’s feet within 28 days, redefined facial contours for a lifted look, enhanced skin resilience and supported tensile strength.


The Lancome Renergie Cream (starts at $56 for 30 ml) concentrates over 300 types of peptides, hyaluronic acid and niacinamide in one unique cream [5].

The peptides in the cream work together to allow the skin to regenerate faster, making wrinkles appear reduced.

Improving the skin’s smoothness, and targeting dark spots specifically, the cream uses HPN 300, Lancome’s complex of 300 peptides to allow the face and neck to feel lifted.

Additionally, the cream shows proven results to increase radiance, extend tone evenness, and correct discolorations.


An AHA-powered moisturizer ideal for mature and dry skin types, the currently sold-out Antipodes Lime Caviar Firming Day Cream ($37 for 60 ml) promotes the illusion of a collagen-rich complexion [6].

The certified organic formula utilizes Sepilift – a pioneering peptide compound – to help improve the look of skin elasticity.

Lipid-rich avocado oil sets to work to smooth the appearance of fine lines, while lime caviar extract refines the skin for a visibly radiant finish.

Scented with a refreshing floral fruity fragrance, the day cream is a luxurious addition to your skincare routine.

It is also certified organic and vegan and suited to all skin types, dehydrated and mature, with antiaging benefits in mind.

This is for all skin types but is specially targeted to more mature skin, which starts to sag and lose its definition. The cream is powered by peptides to revitalize facial definition.


Eucerin has developed a range of skincare aimed explicitly at redefining facial contours and smoothing out fine lines and wrinkles [7].

Oligo peptides, extracted from the fruit and seeds of the anise plant, help the skin’s connective tissue become more robust and stable.

The moisturizer is designed to work while you sleep and utilizes hyaluronic acid to help smooth lines caused by dryness, making your skin look younger, refreshed and revitalized.


Another perpetually sold-out product, Vichy’s Liftactiv Collagen Specialist SPF25 ($53 for 50ml) is the first SPF offering in Vichy’s antiaging range, formulated with key dermatological ingredients including hyaluronic acid, vitamin E and bio-peptides to target signs of collagen loss, while providing broad-spectrum SPF25 protection [8].

The lightweight formula provides hydration that lasts for up to 24 hours: skin looks firmer, plumper and more radiant.

Its ultra-lightweight and fluid texture will glide across the skin effortlessly, leaving it unified, luminous and comfortably moisturized for up to 24 hours.

The Ordinary

The Ordinary Aloe 2% + NAG 2% Solution ($17 for 30ml) is powered by peptide technology (palmitoyl pentapeptide-4) which targets the feel of textural irregularities while offering practical barrier support for blemish-prone and mature skin [9].

The peptide formulation also allows the skin to rejuvenate without disturbing its barrier, so you don’t have to worry about irritation or redness left behind by breakouts.

The soothing water-based serum smooths skin and refines pores by boosting skin hydration. The lightweight formula drenches your skin in calming hydration with aloe barbadensis leaf juice powder.

There you have it, the top six products recommended to rejuvenate your skin and diminish fine lines. Hopefully, this list can be a guide to which peptide skincare products will work best for you.

[1] https://www.mirror.co.uk/3am/style/shopping/6-best-peptide-powered-skincare-30004981
[2] https://www.paulaschoice.com/expert-advice/research-and-education-team
[3] https://www.paulaschoice.com/pro-collagen-multi-peptide-booster/3020-3027.html
[4] http://bitly.ws/ELUb
[5] http://bitly.ws/ELV7
[6] https://antipodesnature.com/products/lime-caviar-collagen-rich-firming-cream-60ml
[7] https://www.eucerinus.com/main-navi-products/face
[8] https://www.vichy-me.com/en-us/Skin-Care/Collagen-Specialist
[9] https://theordinary.com/en-mx/aloe-2-nag-2-solution-blemish-serum-100618.html

The information included in this article is for informational purposes only. The purpose of this webpage is to promote broad consumer understanding and knowledge of various health topics. It is not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.