Best berberine supplement for longevity to buy in 2023

For thousands of years, medicinal plants have been used to treat different ailments, including infections and cancer. Scientists in the past centuries have begun isolating substances and active components of these plants to determine how these work and treat diseases. 

One of the essential compounds isolated from plants includes berberine. Berberine is a naturally occurring compound found in plants such as Coptis, Goldenseal, Oregon grape, Tree Turmeric and Berberry. As an alkaloid, berberine has been shown to have many uses. However, it is toxic to the human body when applied parenterally or on the skin. 

What are some of the actions of berberine? 

Preclinical and several animal model studies have examined the effects of berberine once ingested. Research studies revealed that berberine is quickly absorbed in the small intestine and is transported to different cells in the body through the bloodstream. Interestingly, it works like any other drug once transported inside the cells. It either binds to enzymes or proteins. As one research [1] pointed out, berberine can target critical proteins associated with the spread, invasion, cell growth, cell death and cell cycle arrest. These properties allow berberine to have broad anti-cancer actions by influencing cancer pathways within the cell. 

Interest in natural supplements has dramatically increased due to the fears that long-term use of medicines can lead to adverse effects or side effects and adverse events.
Photograph: Soyka/Shutterstock

Apart from its anti-cancer properties, berberine is effective in the following: 

  • Low cholesterol levels 
  • Delay cognitive decline in patients with dementia 
  • Lower blood pressure levels 
  • Lower blood glucose levels in patients with type 2 diabetes mellitus 

A study [2] affirmed that berberine could lower blood sugar levels by lowering Haemoglobin A1c (HbA1c); fasting blood glucose; plasma triglycerides; and postprandial blood glucose

Choosing the right supplement ensures that you reap the benefits of berberine. 

The good news is these supplements are all within your reach! You can consider the following berberine supplements with their accompanying reviews. 

Toniiq berberine ultra-high purity 

Each capsule of this supplement contains 500 mg of berberine. In contrast with other manufacturers, the makers of this capsule claimed that berberine in the capsules has a purity level of 97%, with its extract of berberine concentrated at least 82 times. Higher purity of the active compound is claimed to increase its absorption in the body. Toniiq berberine is said to be highly absorbed in the body and is beneficial in individuals with type 2 diabetes and those who have high cholesterol and blood pressure. 

Click here to shop Toniiq Berberine ultra-high purity on Amazon.

Thorne berberine dietary supplement 1000 mg 

Thorne contains 1000 mg of berberine per capsule. This supplement is ideal for those who want to take the supplement only once a day. Notably, it does not contain gluten, making it easier for individuals allergic to gluten to take this supplement. It is free from shellfish, fish, soy, dairy, tree nuts and eggs, reducing the risk of allergies to these potential allergens. However, the manufacturers of this supplement failed to declare if berberine is available as berberine HCL to facilitate absorption of the supplement. 

Click here to shop Thorne Berberine 1000mg on Amazon.

Lumanutrition berberine 1200 mg

This supplement also contains berberine HCL, the active form of berberine that can be easily absorbed in the body. Since it contains 1200 mg of berberine HCL per capsule, it allows individuals only to take one capsule per day to reap the benefits of berberine. This makes it easier for those who prefer to take only one capsule of the supplement daily. In some individuals, setting reminders to take a supplement twice a day may result to lower adherence to supplements. Meanwhile, a dose of 1200 mg/day of the supplement is safe and does not lead to adverse reactions. 

Click here to shop Nutrivein Berberine on Amazon.

Nutrivein Premium Berberine HCL 1200 mg Plus Organic Ceylon Cinnamon 

A capsule of this powerful supplement contains 1200 mg of berberine. This is sufficient to reap the benefits of berberine. Research has shown that an intake of 1200 mg of berberine is safe and effective in delaying symptoms of dementia, inducing weight loss and control, lowering blood glucose levels and lowering cholesterol levels. Berberine has been compared to metformin regarding its effects in safely reducing blood glucose. In contrast to metformin, which can have various side effects, natural supplements, such as berberine, have no or minimal side effects. Hence, nutrient-based supplements are now often used to treat common ailments.   

Nutrition premium berberine HCL has added organic Ceylon cinnamon. Cinnamon is another natural antioxidant shown to lower blood glucose levels. Hence, it synergizes with berberine to reduce blood glucose and cholesterol levels. 

Notably, the supplement contains berberine HCL, which is easily absorbed in the body. This is in contrast to berberine alone, which has low bioavailability once taken orally. When combined with HCL, berberine’s absorption is increased and ensures its effectiveness is preserved while absorbed in the body. 

Click here to shop Nutrivein Berberine on Amazon.

Dr. Whitaker’s berberine 1,500 mg supplement 

Each capsule of this dietary supplement contains 1500 mg of berberine. Although it slides not state if berberine is available as berberine HCL, it claims that berberine found in each capsule can be easily absorbed in the body. 

Click here to shop Dr. Whitaker’s berberine on Amazon.

Nutricost Berberine 600 mg 

Nutricost berberine contains berberine HCL, which is essential in increasing the absorption of the supplement in the body. Each capsule contains 600 mg, and when taken twice a day, it would result in a daily intake of 1200 mg. This is within the safe dosage limits for berberine. 

Long-term intake of nutricost berberine has also been shown to be safe, with generally no reported side effects or adverse effects. However, in pregnant patients and older adults, it is advised that these individuals consult with doctors to ensure their safety while taking the supplement. To date, there are still no studies on the effects of berberine on pregnant women and those who are very old. 

Click here to shop Nutricost Berberine on Amazon.

Snap blood sugar blend supplement 

The main component of Snap blood sugar blend supplement includes berberine, cinnamon and 22 active ingredients. Berberine is available as berberine HCL, which ensures its active absorption in the body. 

Apart from berberine, it also contains cinnamon, a known antioxidant that has been shown to improve blood glucose levels. In addition, it contains turmeric, zinc and alpha lipoic acid. Both turmeric and alpha lipoic acids are potent antioxidants and have anti-inflammatory properties. Hence, they are effective in reducing the risk of cardiovascular diseases and type 2 diabetes mellitus and in slowing cognitive decline in those with Alzheimer’s disease. 

Meanwhile, the element zinc is well supported in literature to be effective in boosting the immune system and healing damaged tissues. It acts as a cofactor of several enzymes involved in cell growth and the formation of DNA. 

Click here to shop Snap Blood Sugar Blend Berberine on Amazon.

Nutriflair Premium Berberine + with Ceylon Cinnamon 

Each capsule of this supplement contains berberine HCL at a 1200 mg dose. This makes it ideal for those who want to take only one capsule of the supplement daily. Since berberine is available as berberine HCL, it can be easily absorbed in the body and promote its benefits from type 2 diabetes control to weight loss control. 

Notably, the supplement likewise contains cinnamon, which is another antioxidant. Furthermore, cinnamon has anti-inflammatory properties. Together with berberine HCL, it can further promote weight loss and control in those who want to maintain a healthy weight range. 

Click here to shop Nutriflair Premium Berberine on Amazon.

[1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691338/
[2] https://www.sciencedirect.com/science/article/abs/pii/S0944711322001775

Photograph: Amtiko/Shutterstock
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