Hyaluronic acid: Benefits, side effects, uses, risks, types

Hyaluronic acid has quietly taken center stage in the beauty and health sectors, celebrated for its remarkable ability to hydrate skin, ease joint pain, and much more.

This naturally occurring molecule, found in our skin, eyes, and joints, plays a crucial role in maintaining moisture and ensuring our body’s tissues operate smoothly.

As we age, our natural reserves of hyaluronic acid begin to deplete, leading to common aging signs like wrinkles and joint discomfort.

Fortunately, science has found ways to harness the power of hyaluronic acid, offering it in various forms such as serums, supplements, and injections. These products promise not only to replenish lost moisture but also to revitalize our overall well-being.

What does hyaluronic acid do for the skin?

Hyaluronic acid (HA) is a bit of a superstar in the wellness and beauty worlds, and for good reasons [1]. This naturally occurring substance has some pretty impressive benefits for your skin, joints, and overall health.

Let’s talk about why hyaluronic acid has become a go-to ingredient in skin care products and health supplements and how it can make a difference in your life.

Keeps skin hydrated

Hyaluronic acid is a hydration hero for your skin, offering a boost of moisture and helping to maintain a youthful, resilient appearance. 

This powerhouse molecule can hold up to 1,000 times its weight in water, deeply hydrating the skin and preventing moisture loss. This means your skin stays hydrated, plump, and soft throughout the day.

Regular use of hyaluronic acid can smooth out the skin’s surface, giving you a silky, more refined texture. It fills in fine lines and makes your skin feel incredibly soft.

Hyaluronic acid helps replenish the skin’s natural elasticity, making it look firmer and more toned. This is essential for keeping your skin looking youthful and reducing the appearance of wrinkles and fine lines.

It can be used on any type of skin, even sensitive skin. It is a versatile complement to any skincare routine because it hydrates without blocking pores or triggering breakouts.

Beyond just superficial benefits, hyaluronic acid supports the skin’s barrier function, protecting against environmental stressors and pollutants. This contributes to overall skin health and resilience.

Incorporating hyaluronic acid into your skincare routine is a simple step with significant benefits, ensuring your skin remains hydrated, elastic, and radiant.

skin hydration and elasticity

Soothes dry skin and eczema

Hyaluronic acid stands out as a soothing balm for those grappling with dry skin and eczema. Its unique properties offer relief and healing to irritated skin. 

It penetrates the skin, providing deep hydration that soothes dryness and flakiness [2]. It helps maintain the skin’s moisture balance, offering relief from the tight and uncomfortable feeling of dry skin.

Its anti-inflammatory properties help calm eczema flare-ups, reducing redness and irritation. This makes hyaluronic acid a gentle yet effective ingredient for sensitive skin conditions.

By enhancing the skin’s natural barrier, hyaluronic acid protects against environmental aggressors that can worsen dry skin and eczema. A stronger barrier retains more moisture, keeping the skin hydrated and healthy.

For eczema sufferers, hyaluronic acid can accelerate the healing of damaged skin, encouraging faster recovery from flare-ups and reducing the likelihood of infection.

Applying hyaluronic acid to dry or eczematous skin provides immediate relief, leaving the skin feeling soothed and comfortable. It’s like a comforting hug for your skin, easing discomfort and promoting well-being.

Incorporating hyaluronic acid into your skincare routine can be a game-changer for managing dry skin and eczema, offering a path to healthier, more comfortable skin.

Accelerates wound healing

Hyaluronic acid is not just a skincare superstar; it’s also a key player in accelerating wound healing. It encourages the growth of new skin cells, speeding up the healing process. This regeneration is crucial for wounds to close and heal properly.

It effectively reduces inflammation around wounds, preventing excessive swelling and pain. This controlled inflammation is essential for a healthy healing environment.

Keeping the wound area moist is vital for healing. Hyaluronic acid ensures the wound bed remains hydrated, which is crucial for cell migration and wound repair.

The growth of new blood vessels, or angiogenesis, is critical for delivering nutrients to the wound site. Hyaluronic acid aids this process, ensuring the wound receives the nourishment it needs to heal.

Applying hyaluronic acid to wounds can help protect them from infection and external aggressors, providing a safe environment for the healing process.

By incorporating hyaluronic acid into post-injury care, you can significantly improve the healing time and outcome of wounds, making it a valuable ally in your body’s repair toolkit.

Enhances nutrient delivery to the skin

Hyaluronic acid doesn’t just hydrate your skin; it also enhances the delivery of essential nutrients, ensuring your skin receives the nourishment it needs to thrive. 

Hyaluronic acid acts as a carrier, helping other beneficial ingredients penetrate deeper into the skin. This means that when you use skincare products containing HA, your skin can better absorb vitamins, antioxidants, and other nutrients, maximizing their effectiveness.

By locking moisture into the skin, hyaluronic acid creates a reservoir that holds onto those nutrients, preventing them from evaporating or being washed away. This prolonged exposure to nutrients allows for more significant improvements in skin health over time.

With enhanced absorption and retention, the active ingredients in your skincare products can work more efficiently, delivering visible results like improved texture, tone, and overall radiance.

Incorporating hyaluronic acid into your skincare routine isn’t just about hydration; it’s also about optimizing nutrient delivery for healthier, more vibrant skin.

Safe for most skin types

When it comes to skincare, hyaluronic acid is a crowd-pleaser, suitable for most skin types. Hyaluronic acid’s lightweight texture makes it suitable for even the most sensitive skin types. It hydrates without feeling heavy or greasy, making it a favorite among those prone to breakouts or irritation.

Unlike some moisturizers or oils that can clog pores and lead to breakouts, hyaluronic acid is non-comedogenic. It won’t block your pores, making it ideal for oily or acne-prone skin.

Whether you have dry, oily, or combination skin, hyaluronic acid adjusts to your skin’s needs, providing just the right amount of hydration without overdoing it [3].

Its natural presence in the body means that hyaluronic acid is generally well-tolerated, even by those with sensitive or reactive skin. It is unlikely to result in allergic reactions or irritation.

Regardless of your skin type, adding hyaluronic acid to your skincare regimen is an easy approach to hydrate and nourish your skin.

Does hyaluronic acid have any side effects?

While HA is generally well-tolerated by most people, it’s essential to be aware of possible adverse reactions, especially when using it in high concentrations or in certain forms like injections. Here’s what you need to know:

Acne breakouts

Let’s tackle a pesky issue: acne breakouts. While Hyaluronic acid (HA) is generally skin-friendly, it might not play nice with everyone’s skin, especially if you’re prone to pimples. Here’s what could happen:

  • Increased breakouts: Some folks find that using HA-rich products leads to more pimples popping up. It’s frustrating, we know, but your skin might need a different approach.
  • Clogged pores: Even though HA is non-comedogenic, meaning it shouldn’t clog pores, it can still team up with other ingredients to create a perfect storm for breakouts.
  • Potential culprits: Check your product labels for any comedogenic ingredients that might be causing trouble. Sometimes it’s not the HA itself, but what it’s mixed with that’s the problem.

If you’re battling breakouts, try switching to HA-free products for a while and see if your skin calms down. And as always, a chat with a dermatologist can help pinpoint the culprit and find a solution.

Skin irritation

It’s important to note that hyaluronic acid (HA) is generally gentle, but some people may experience mild skin irritation. Here’s what you need to know:

  • Redness: Your skin might flush a bit, turning pink or even slightly red in response to HA. It’s usually temporary and nothing to worry about.
  • Itching: Some people may feel a slight itchiness after applying HA products. It’s annoying, sure, but it usually fades away quickly [4].
  • Tingling sensation: A tingling or prickling sensation on the skin is another common reaction. It’s like a little reminder that your skin is getting a boost of hydration.

If you experience any of these symptoms, don’t panic. Simply ease up on the HA for a bit or switch to a lower concentration product. And if the irritation persists or worsens, it’s always wise to seek advice from a dermatologist.

Allergic reactions

Let’s talk about a less-than-pleasant possibility: allergic reactions to hyaluronic acid (HA). While rare, they can happen, and it’s essential to know the signs:

  • Hives: If you notice itchy, raised welts on your skin after using HA, it could be a sign of an allergic reaction. These hives can range from mild to severe and may spread across the body.
  • Swelling: Your skin, lips, or even your throat might swell up after coming into contact with HA. This swelling can be alarming and may indicate a more severe allergic response.
  • Difficulty breathing: In severe cases, an allergic reaction to HA can cause difficulty breathing or tightness in the chest. This is a medical emergency and requires immediate attention.

If you experience any of these symptoms after using HA, stop using it immediately and seek medical help. It’s always better to be safe than sorry when it comes to allergies.

How should I use hyaluronic acid?

Hyaluronic acid, a versatile compound, serves as a powerhouse ingredient in skincare, offering hydration, anti-aging benefits, and soothing properties.

Beyond skincare, hyaluronic acid finds applications in medicine, aiding joint health, eye care, and wound healing with its lubricating and moisturizing properties.

Skincare uses

In your regular skincare regimen, hyaluronic acid (HA) can do wonders for your skin. HA is like a drink of water for your skin, quenching its thirst and keeping it plump and hydrated throughout the day.

By retaining moisture, HA helps smooth out fine lines and wrinkles, giving your skin a more youthful appearance.

If you have sensitive or irritated skin, HA can help calm redness, inflammation, and itching, leaving your skin feeling comfortable and happy. HA acts as a booster, helping other skincare ingredients penetrate deeper into your skin for maximum effectiveness.

Whether it’s a minor scrape or a more significant injury, HA promotes faster healing and reduces scarring, making it an essential ingredient in your first-aid kit.

Medical and therapeutic uses

Here are some examples of the significant medical and therapeutic applications of hyaluronic acid (HA), which goes beyond skincare:

  • Joint health: HA injections lubricate and cushion the joints, providing relief for conditions like osteoarthritis and improving mobility [5].
  • Eye health: HA eye drops moisturize and soothe dry eyes, while HA is also used in certain eye surgeries to protect delicate tissues.
  • Dermal fillers: HA-based fillers plump up the skin, smooth out wrinkles, and restore facial volume, providing a youthful appearance.
  • Oral supplements: HA supplements support skin health, joint function, and overall hydration from within, promoting well-being.
  • Dental care: HA in mouthwashes and toothpaste moisturizes oral tissues, relieving dry mouth and promoting oral health.

From easing joint pain to protecting delicate eye tissues, hyaluronic acid offers a range of therapeutic benefits beyond its skincare prowess.

Medical and therapeutic uses

Miscellaneous uses

Let’s look at some surprising applications for hyaluronic acid (HA) that go beyond cosmetics and health care:

  • Hair care: HA-infused shampoos, conditioners, and styling products hydrate the scalp and hair, leaving it soft, shiny, and more manageable.
  • Wound dressings: In order to create a moist environment that aids in healing and keeps the wound from drying up, HA is utilized in bandages and wound dressings.
  • Cosmetics: HA is a common ingredient in cosmetics like foundation, primer, and lipstick. It smooths out the skin’s surface, provides hydration, and improves the texture and appearance of makeup.
  • Personal lubricants: HA-based lubricants provide long-lasting moisture and glide, making them a popular choice for intimate use.

From hair care to wound healing, hyaluronic acid offers a diverse range of applications beyond its traditional uses in skincare and medicine.

Can hyaluronic acid injections go wrong?

Let’s explore the potential risks associated with hyaluronic acid (HA) injections, offering insights into the safety considerations of this popular cosmetic procedure.

Understanding these risks can help individuals make informed decisions about their aesthetic treatments and prioritize their health and well-being.

Injection site reactions

The common occurrence of injection site reactions following hyaluronic acid (HA) injections. These reactions typically manifest as temporary redness, swelling, and tenderness at the injection site, similar to a mild bruise. 

While they may cause discomfort initially, these reactions usually subside within a few days as the body absorbs the injected HA and the skin heals naturally. If you experience any unusual or severe reactions, it’s essential to contact your healthcare provider promptly for further guidance and reassurance.

Bruising and discoloration

A common side effect of hyaluronic acid (HA) injections. After the procedure, it’s normal to notice some bruising and skin discoloration around the injection site.

This typically resolves on its own within a few days, but you can help speed up the healing process by applying cold compresses and avoiding strenuous activities.

If the bruising persists or you have any concerns, don’t hesitate to reach out to your healthcare provider for guidance.

Migration or misplacement 

The potential for migration or misplacement of hyaluronic acid (HA) filler following injections. Sometimes, the filler may move from the intended injection site, leading to asymmetry or unintended results.

While this occurrence is rare, it’s crucial to ensure that your healthcare provider is skilled and experienced in administering HA injections to minimize the risk of such complications [6]. 

If you notice any unusual changes in the appearance of your skin after treatment, it’s essential to contact your provider for further assessment and possible corrective measures.

What type of hyaluronic acid is best?

Discover the diverse world of hyaluronic acid, ranging from injectable fillers to oral supplements, each offering unique benefits for skincare and overall well-being.

Explore the varied applications and formulations of this versatile ingredient in our comprehensive guide to the types of hyaluronic acid.

Sodium hyaluronate 

Sodium hyaluronate is a salt form of hyaluronic acid known for its smaller molecular size, which allows it to penetrate the skin more effectively.

This powerhouse ingredient is a hydration hero, drawing moisture into the skin and locking it in for a plump, dewy complexion. It’s like a tall glass of water for your skin cells!

You’ll find sodium hyaluronate in various skincare products, from lightweight serums to rich moisturizers. It’s suitable for all skin types and can be used daily for a boost of hydration.

With sodium hyaluronate on your side, your skin will be well-hydrated, smooth, and radiant—ready to take on whatever the day brings!

Hyaluronic acid fillers

Hyaluronic acid fillers are injectable gels made from cross-linked HA molecules, designed to add volume, smooth out wrinkles, and enhance facial features.

These fillers provide immediate results, plumping up the skin and reducing the appearance of fine lines and wrinkles. They’re a non-surgical option for facial rejuvenation, with minimal downtime and natural-looking results.

Whether you’re looking to enhance your lips, define your cheekbones, or soften nasolabial folds, hyaluronic acid fillers offer customizable options to suit your needs [7].

With hyaluronic acid fillers, you can achieve a refreshed, youthful appearance without going under the knife—just a quick trip to your dermatologist or cosmetic injector!

Hyaluronic acid supplements

Hyaluronic acid supplements come in pill or liquid form and are taken orally to promote skin hydration, joint health, and overall well-being.

These supplements provide an easy and accessible way to increase your body’s hyaluronic acid levels, supporting skin moisture and elasticity while also lubricating and cushioning the joints.

Whether you’re dealing with dry, dull skin or joint discomfort, hyaluronic acid supplements offer a simple solution to help you look and feel your best from the inside out.

Incorporating hyaluronic acid supplements into your daily routine can be a game-changer for maintaining healthy, hydrated skin and flexible, pain-free joints.

Hyaluronic acid eye drops

Hyaluronic acid eye drops are sterile solutions containing HA as the active ingredient, designed to moisturize and lubricate the surface of the eye.

These eye drops provide immediate relief from dryness, irritation, and discomfort, leaving your eyes feeling refreshed and revitalized.

Whether you’re spending long hours staring at screens or dealing with environmental factors like wind and air conditioning, hyaluronic acid eye drops offer soothing relief whenever your eyes need a pick-me-up.

HA eye drops are safe for use with contact lenses and are suitable for individuals with sensitive eyes, making them a convenient choice for daily eye care.

With hyaluronic acid eye drops, you can say goodbye to dry, uncomfortable eyes and hello to clear, hydrated vision.

Hyaluronic acid injections for joints

Hyaluronic acid injections involve injecting HA directly into the joint space to improve lubrication and reduce pain and inflammation [8].

These injections provide significant pain relief and improve joint function, allowing individuals to engage in daily activities with greater ease. They’re considered safe and well-tolerated, with minimal side effects.

Whether you’re dealing with osteoarthritis in your knees, hips, or shoulders, hyaluronic acid injections offer targeted relief right where you need it most.

With hyaluronic acid injections, you can kiss joint pain goodbye and get back to doing the things you love without hesitation.

Closing thoughts

Hyaluronic acid (HA) offers a range of benefits for skincare and medical purposes, from improving skin hydration and elasticity to accelerating wound healing and enhancing joint health.

However, it’s essential to be aware of the potential side effects and risks associated with HA treatments, such as injection site reactions, bruising, and migration. Despite these risks, when administered by a qualified healthcare professional, HA injections can be safe and effective.

By taking these proactive steps, you can make informed decisions about incorporating HA treatments into your skincare or medical regimen. Remember, your safety and well-being are paramount, so prioritize thorough research and consultation with a healthcare professional before undergoing any treatment.


What are the benefits of hyaluronic acid for skincare?

Hyaluronic acid helps retain moisture in the skin, resulting in improved hydration, plumpness, and reduced appearance of fine lines and wrinkles. It also promotes a smoother, more radiant complexion.

Are there any side effects to using hyaluronic acid in skincare products?

While hyaluronic acid is generally safe, some individuals may experience mild irritation or allergic reactions. It’s essential to patch-test new products and consult with a dermatologist if you have sensitive skin or any concerns.

How often should I use hyaluronic acid in my skincare routine?

You can use hyaluronic acid daily, both morning and night, depending on your skin’s needs. It’s versatile and can be incorporated into your routine as a serum, moisturizer, or even mixed with other products.

[1] https://greatist.com/health/hyaluronic-acid-benefits
[2] https://www.amberbudd.com/hyaluronicacid
[3] https://www.healthline.com/health/beauty-skin-care/hyaluronic-acid
[4] https://www.healthline.com/health/itching
[5] https://www.gulfwestmedicalassociates.com/blog/how-hyaluronic-acid-injections-can-alleviate-arthritic-knee-joint-pain
[6] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5172480/
[7] https://www.vargasfaceandskin.com/choosing-the-right-facial-filler-for-your-skin-type/
[8] https://my.clevelandclinic.org/health/articles/22915-hyaluronic-acid

The information included in this article is for informational purposes only. The purpose of this webpage is to promote broad consumer understanding and knowledge of various health topics. It is not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.