Is allulose safe for diabetics? Here’s what the research says

How often do you come across a sweetener that is suitable for managing diabetes? With diabetes affecting millions globally, the challenge of finding safe and effective sugar alternatives is more pressing than ever. 

Allulose, a groundbreaking sweetener, offers a glimmer of hope. It can sweeten without the usual spike in blood glucose levels. 

This blog dives into the heart of the matter, examining allulose’s safety for diabetics and its potential impact, all backed by the latest scientific research. 

Join us as we explore this promising sugar alternative and its role in diabetes management.

Is allulose OK for diabetics?

Allulose, a revolutionary sweetener, might be the game-changer you’re searching for in your diet, especially if managing diabetes is a priority. 

This natural sugar found in small quantities in fruits like figs and raisins [1] is making a significant impact due to its unique properties. 

Unlike traditional sugar, allulose boasts a sweetness profile similar to sucrose (table sugar) but comes with a fraction of the calories. 

This means you can enjoy the sweet flavors you love without the calorie guilt or fear of spiking your blood sugar levels.

Allulose’s minimal impact on blood glucose levels sets it apart from other sweeteners. For individuals with diabetes, this is critical, as managing blood sugar is a daily balancing act. 

Allulose is a sweetener with a zero glycemic index (GI) [2]. This means consuming it does not cause a spike in blood glucose or insulin levels. This makes allulose an excellent option for people who want to limit their sugar consumption while still enjoying the taste of sweet foods.

Moreover, its low-calorie count—approximately 1/10th the calories of regular sugar—further enhances its appeal. 

This combination of low calories and negligible blood sugar impact makes allulose a sweetener and a strategic ally in diabetes management and weight control.

How does allulose affect diabetics?

One of the most promising aspects of allulose for people with diabetes is its potential impact on blood sugar control. 

Research indicates that allulose has minimal effect on blood sugar levels due to its unique absorption and metabolism by the body, unlike most sugars [3].

While most sugars are readily digested and absorbed, leading to a spike in blood sugar, allulose passes through the digestive system undigested.

To better understand, it’s important to know the glycemic index (GI) values of different foods as they impact blood sugar levels.

Foods with a high GI cause a rapid increase in blood sugar [4], while those with a low GI have a minimal effect. Remarkably, allulose has a GI of zero, indicating no impact on blood sugar levels.

This unique property of allulose holds potential benefits for people with diabetes. Studies show that allulose consumption may improve glucose tolerance, meaning the body can effectively utilize blood sugar [5]. 

Additionally, some research suggests that allulose may help reduce insulin resistance [6], a condition where the body’s cells become less responsive to insulin, further contributing to high blood sugar levels. 

While further research is ongoing, these findings are encouraging and suggest that allulose could be a valuable tool in managing blood sugar levels for diabetics.

How does allulose affect diabetics?

Is allulose safe?

Allulose is generally considered safe for consumption by most individuals, with studies supporting its safety profile. 

The FDA has granted it the Generally Recognized As Safe (GRAS) status, signifying its approval for use in food products [7].

However, it’s important to remember that moderation is key, even with safe substances. 

Excessive intake of allulose can lead to digestive issues like abdominal pain, nausea, and diarrhea [8]. This is because our bodies are not fully accustomed to digesting allulose, which may pass through the digestive system undigested, causing these side effects.

Therefore, practicing moderation is crucial, especially when introducing allulose into your diet. It’s recommended to start with small amounts and gradually increase intake as tolerated. 

It’s also advisable to consult a healthcare provider before making any significant changes to your diet, including adding allulose. 

This is especially important if you have underlying health conditions, are pregnant or breastfeeding, or are taking medications. 

They can help you determine if allulose is a safe and suitable option and advise on appropriate consumption levels.

How does allulose compare with other sugar alternatives in a diabetic diet?

While allulose shows promise for diabetics, it’s not the only sugar alternative on the market.

Here’s a breakdown of allulose against three popular alternatives: Stevia, erythritol, and sucralose.


Allulose offers a moderate sweetness, around 70% that of sugar, making it suitable for those seeking a more natural taste. 

On the other hand, Stevia, on the other hand, is significantly sweeter (200-300 times) [9] and requires minimal use to achieve the desired sweetness. Erythritol and sucralose are also intensely sweet, varying slightly in taste profile.


Allulose and erythritol have negligible calorie content, making them ideal for weight management. 

Stevia also boasts minimal calories, although some Stevia products blended with other ingredients may contribute calories. 

Sucralose provides negligible calories but may not be suitable for weight management due to potential appetite-stimulating effects [10] observed in some studies.

Glycemic Index (GI)

Allulose stands out with a GI of zero, indicating no impact on blood sugar, making it a safe option for diabetics. Erythritol also has a very low GI, making it suitable for blood sugar control. 

Stevia has a minimal impact on blood sugar in healthy individuals, but its effect on diabetics might vary depending on individual factors. Sucralose, while calorie-free, has a GI of around 60, causing a moderate rise in blood sugar.

Side effects

Excessive consumption of sugar substitutes can lead to digestive issues like bloating and gas. 

While generally well-tolerated, allulose may cause these issues in some individuals, especially at higher intakes. 

Erythritol is well-tolerated but may cause side effects at high doses. For some, Stevia can have a bitter aftertaste, and sucralose may leave an unpleasant aftertaste in certain individuals.

Unique advantages and limitations

Allulose’s key strengths are its natural sugar-like taste and minimal impact on blood sugar. However, its limited availability and higher cost compared to some alternatives might be drawbacks. 

Stevia offers intense sweetness and is readily available, but its potential variability in blood sugar effects and aftertaste requires individual consideration. 

Erythritol provides a clean taste and low GI but may cause side effects at high doses. 

Sucralose is calorie-free [11] but has a higher GI and potential appetite-stimulating effects, making it less suitable for certain diabetic goals.

Ultimately, the best choice depends on your preferences and diabetic management goals. Before incorporating any new sweetener into your diet, consult a healthcare professional for personalized guidance.

Practical tips for diabetics considering allulose

Practical tips for diabetics considering allulose

While allulose shows promise for blood sugar management, it’s crucial to remember it’s not a free pass to indulge in sugary treats. 

Here are some practical tips for incorporating allulose into your diabetic diet safely and effectively:

1. Integrate mindfully

Allulose may not directly raise blood sugar but can still add to your overall calorie intake. Be mindful of the amount and avoid using it excessively in place of sugar, which can lead to unwanted weight gain.

2. Read labels carefully

When shopping for allulose-containing products, become a label-reading pro. Allulose may be listed under its name or as “allulose syrup.” Scrutinize the entire ingredient list, not just focusing on the presence of allulose, to ensure the product aligns with your overall dietary goals.

3. Monitor your blood sugar

Even with the minimal impact expected, it’s advisable to closely monitor blood sugar levels when introducing allulose, especially if managing diabetes with insulin or medications. This helps you understand its impact on your blood sugar control.

4. Consult your healthcare provider

Before incorporating any new sweetener, including allulose, into your diabetic diet, it’s essential to consult with a healthcare professional or registered dietitian. Considering your needs and medical history, they can guide you on appropriate usage.

Closing thoughts

Allulose is a promising option for diabetics. It offers sweetness with minimal impact on blood sugar. Research suggests it can improve glucose tolerance and even reduce insulin resistance. 

However, it’s crucial to remember that moderation is key, and potential side effects like bloating may occur with excessive consumption. 

Consulting a healthcare professional before incorporating allulose into your diabetic diet is vital to ensure its safety and suitability for your individual needs. 

Remember, a balanced diet and proper medical guidance remain essential for effective blood sugar management.


Does allulose spike glucose?

No, allulose does not spike glucose levels. Unlike most sugars, it is not fully absorbed by the body, resulting in minimal impact on blood sugar.

Does allulose affect insulin levels?

Allulose may have a minimal initial effect on insulin levels, but studies suggest it does not significantly raise them like traditional sugars. Further research is needed to fully understand its long-term impact.

What is the safest sugar substitute for diabetics?

Due to ongoing research and individual variations, there isn’t a single “safest” sugar substitute for all people with diabetes. Consulting a healthcare professional is crucial to determine the most suitable option for your needs and health conditions.

What can you substitute for allulose?

If you can’t find allulose, other sugar substitutes with minimal blood sugar impact, like erythritol, Stevia, or monk fruit extract, can be options. Remember to consult a healthcare professional before making changes to your diet, especially if you have diabetes.


The information included in this article is for informational purposes only. The purpose of this webpage is to promote broad consumer understanding and knowledge of various health topics. It is not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.