Scientists discover pain feels different for men and women

A groundbreaking study published in Brain has revealed that men and women experience pain differently due to distinct neural pathways in their brains.

The study subjected participants to pain stimuli while monitoring their brain activity [1]. The results showed that men and women activated different brain regions in response to the same painful stimuli.

Specifically, women showed more significant activity in the limbic system, which is associated with emotional processing. In contrast, men exhibited more activity in the sensorimotor regions, which are linked to physical sensation and action.

These differences suggest that men and women benefit from different pain management approaches [2]. For example, treatments targeting emotional aspects of pain may be more effective for women, while men respond better to therapies focusing on physical sensation.

This personalized approach to pain management could enhance the efficacy of treatments and improve patient outcomes.

This study is essential for both clinical practice and future research. Traditionally, pain research and treatment have not adequately considered sex differences, potentially leading to less effective pain management strategies [3].

By recognizing and addressing these differences, healthcare providers can develop more targeted and effective treatments for pain.

In addition, this research highlights the importance of including both men and women in clinical trials better to understand sex-specific responses to pain and other medical conditions.

Future studies could explore factors influencing pain perception, such as hormonal fluctuations and genetic differences, to refine personalized treatment strategies.

This study demonstrates that men and women experience pain through different neural mechanisms. These findings highlight the need for personalized pain management approaches that consider sex differences, ultimately aiming to improve treatment outcomes for both men and women.


The information included in this article is for informational purposes only. The purpose of this webpage is to promote broad consumer understanding and knowledge of various health topics. It is not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.