Vitamin E vs Vitamin C: Which is best for your skin?

Achieving and maintaining radiant, healthy skin requires carefully curated nutrients, and vitamins C and E consistently emerge as essential components in skincare.

Research indicates that vitamin C’s anti-inflammatory properties effectively improve the appearance of wrinkles, shield the skin from harmful UV rays, reduce dark spots, and ease acne [1].

On the other hand, vitamin E is celebrated for its ability to protect against sun damage, diminish the signs of photoaging, stimulate collagen synthesis, and prevent collagen degradation [2].

Together, these two vitamins form a powerhouse duo that synergistically enhances UV protection and improves the skin’s biomechanical qualities [3]. This blog explores the unique and combined benefits of vitamins C and E, offering you guidance in your journey toward vibrant, youthful skin.

What are the differences between Vitamin E and Vitamin C?

Vitamins E and C are potent antioxidants that play crucial roles in skincare but function differently.

Vitamin E, a fat-soluble antioxidant, helps repair skin cells and protects against free radicals that can cause damage. It is especially known for its photoprotective qualities, reducing the effects of sun damage and enhancing collagen synthesis.

Vitamin C, a water-soluble antioxidant, is essential for collagen production, reduces wrinkles, fades dark spots, and combats inflammation.

While each vitamin has its own unique properties, understanding their differences can help you decide which one (or both) is best suited for your specific skincare needs.

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Chemical composition and properties

AspectVitamin EVitamin C
Chemical structureSix-carbon ring, water-solubleChromanol ring with a hydrophobic side chain, fat-soluble
Antioxidant functionPowerful antioxidant, donates electrons to neutralize free radicals, particularly effective against oxidative stress caused by pollution and UV lightProtects skin cells from oxidative damage by donating electrons to neutralize free radicals, particularly those caused by UV radiation and environmental stressors
Collagen synthesisEssential for collagen production, improves skin firmness and reduces wrinklesEnhances collagen synthesis and inhibits collagen degradation, promoting skin elasticity
Skin barrier supportHelps maintain healthy skin by improving skin barrier function, but primarily aids collagen synthesis for structureEnhances the natural skin barrier, locks in moisture, and improves hydration levels, especially beneficial for dry or sensitive skin
Anti-inflammatory effectsReduces inflammation, particularly effective against acne and reducing dark spotsSoothes irritated skin due to its anti-inflammatory properties, especially helpful for conditions like eczema
Photoprotective propertiesOffers some protection against UV rays by reducing free radicals and sun damage when used with sunscreenStrong photoprotective effect, reduces signs of photoaging, and provides synergistic UV protection when combined with Vitamin C

Absorption and bioavailability

AspectVitamin EVitamin C
AbsorptionWater-soluble and absorbed in the small intestine via active transport and passive diffusionFat-soluble and requires dietary lipids for optimal absorption
BioavailabilityInfluenced by dosage, diet, and individual differences; High doses can lead to reduced bioavailability.Varies by form and source; Natural forms (d-alpha-tocopherol) are more bioavailable than synthetic ones (dl-alpha-tocopherol).
Vitamin E
Photograph: microgen/Envato

What are the skin benefits of vitamin E?

There are several advantages of vitamin E for the skin. Vitamin E is extremely important for preserving healthy and youthful skin because of its powerful antioxidant capabilities and capacity to speed up skin repair. 

Let’s examine the numerous ways that vitamin E might improve the health of your skin:

Protection against oxidative stress

Strong antioxidant vitamin E fights free radicals produced by environmental stresses, including UV radiation, pollution and sedentary lifestyle choices like smoking. 

Vitamin E prevents oxidative damage to skin cells by scavenging free radicals, which lowers the risk of premature aging and supports a youthful appearance.

Defense against UV damage

Sunscreen and vitamin E combine to offer a stronger defense against the damaging effects of UV radiation. Its assistance in quenching free radicals produced by UV exposure decreases the risk of sunburn and long-term UV-induced skin damage.

Enhanced skin barrier function

Vitamin E supports the skin’s natural barrier, limiting moisture loss and preserving the skin’s ideal hydration levels. Balancing the skin’s total moisture content can aid those with dry or dehydrated skin.

Soothing and calming properties

Vitamin E’s anti-inflammatory qualities make it useful for healing and relaxing inflamed or sensitive skin [4]. It can also reduce the irritation, itching and redness of several skin disorders, including eczema and dermatitis.

Promotion of wound healing

Vitamin E promotes collagen synthesis, a protein necessary for wound repair, speeding up healing. Cuts, burns, and other skin injuries can heal faster because of their assistance in promoting tissue regeneration and speeding up the creation of new skin cells.

Scar reduction

By encouraging healthy skin cell turnover and reducing the production of scar tissue, regular topical use of vitamin E may help fade the appearance of scars. Over time, it can assist in making stretch marks, acne scars, and surgical scars less noticeable.

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What are the skin benefits of vitamin C?

Vitamin C’s strong skin benefits are well known. Due to its powerful antioxidant action and contribution to collagen formation, vitamin C is essential for supporting healthy and bright skin. 

Let’s look at some of the ways Vitamin C might help your skin:

Protection against free radicals

Strong antioxidant vitamin C works to combat free radicals and lessen oxidative stress on the skin [5].

Vitamin C contributes to the preservation of the skin’s youthful appearance and delays premature aging by reducing the harm caused by external aggressors such as UV rays, environmental toxins and other irritants.

Defense against sun damage

Vitamin C is improved for sun protection when used in conjunction with sunscreen. It lessens the chance of getting sunburned and helps prevent the creation of free radicals caused by UV exposure. 

Vitamin C may also aid in the fading of sunspots and hyperpigmentation brought on by sun damage.

Boosts collagen production

Collagen production, a critical step that gives the skin structural support, depends on vitamin C. Collagen maintains the skin’s suppleness and firmness, and Vitamin C is essential for its synthesis. 

Vitamin C promotes collagen formation, which helps to enhance skin texture and lessen the visibility of fine lines and wrinkles.

Enhances skin firmness

Vitamin C can help enhance collagen synthesis, which helps the skin become more elastic and firm and gives it a more youthful appearance [6]. It helps restore a more elevated look and fight sagging skin.

Evens out skin tone

Thanks to vitamin C’s skin-brightening abilities, dark spots, age spots, and hyperpigmentation might be less noticeable. It promotes a more even complexion by preventing the formation of melanin, the pigment that gives skin its color.

Radiant and glowing skin

Vitamin C can assist in revealing skin that is more luminous and radiant by encouraging cell turnover and exfoliation. It can enhance the overall brightness of your skin and give your face a healthy shine.

Antioxidant repair

Vitamin C helps repair and prevent UV radiation damage. It also makes long-term sun damage less likely since it reverses the damaging effects of sun exposure and repairs the skin’s DNA.

Reduction of photoaging signs

Vitamin C can reduce fine lines, wrinkles, and other symptoms of photoaging, like discoloration. It enhances the skin’s natural healing mechanisms and encourages cell renewal.

What are the skin benefits of vitamin C?

Myths about Vitamin E and Vitamin C

Misconceptions about vitamins C and E in skincare can often lead to ineffective use or missed opportunities for healthier skin [7], [8].

The following table addresses prevalent myths surrounding both vitamins, clarifying their actual effects and how they can be optimally used.

From concerns about skin sensitivity to the timing and combination of applications, this comparison aims to dispel these myths and empower you with accurate information to enhance your skincare regimen.

AspectVitamin EVitamin C
Skin sensitivityMyth: Vitamin C increases skin sensitivity.
Reality: In its pure form, vitamin C can cause irritation in high concentrations or on sensitive skin, but milder derivatives are available and suitable for all skin types.
Myth: Vitamin E is suitable for all skin types.
Reality: While vitamin E is generally considered gentle, some individuals can develop contact dermatitis or irritation, especially if they have sensitive skin or certain allergies.
Skin type suitabilityMyth: Vitamin C is only beneficial for aging skin.
Reality: Vitamin C can also help with hyperpigmentation, acne, and dullness in younger skin, making it suitable for various age groups and skin concerns.
Myth: Vitamin E is only beneficial for dry skin.
Reality: Vitamin E’s antioxidant and soothing properties benefit other skin types, including oily and combination skin.
Application timingMyth: Vitamin C should only be used in the morning.
Reality: Although it’s beneficial in protecting against UV damage when used during the day, vitamin C can be effective at night due to its regenerative properties.
Myth: Vitamin E is best applied at night only.
Reality: Applying vitamin E both day and night offers continuous antioxidant protection and moisture retention, especially in combination with sunscreen during the day.
Combination with other ingredientsMyth: Vitamin C cannot be used with retinol or niacinamide.
Reality: When used properly, vitamin C can be beneficial alongside these ingredients, helping to brighten and regenerate the skin.
Myth: Vitamin E should not be combined with other oils.
Reality: When blended carefully with oils like jojoba or argan, vitamin E can help improve skin hydration and provide added antioxidant protection.

How to choose the right vitamin for your skin?

Your specific skin care demands and objectives should be considered while choosing the best vitamin for your skin. 

Both vitamin E and vitamin C have various advantages, but knowing which ones they have in particular will help you make an educated decision [9]. Consider the following while selecting the best vitamin for your skin:

Dry skin

Due to its hydrating qualities, Vitamin E might be especially helpful for dry skin. It aids in hydrating and nourishing the skin, enhancing its general texture and reducing dryness.

Aging skin

Vitamin E and Vitamin C are both crucial in the fight against aging. However, due to its capacity to increase collagen, vitamin C is particularly beneficial for treating fine lines, wrinkles, and elasticity loss caused by aging skin.

Sensitive skin

The calming and anti-inflammatory qualities of vitamin E might be helpful for those with sensitive skin. It lessens redness and irritation while protecting and calming the skin.


Vitamin C is highly beneficial for treating hyperpigmentation and uneven skin tone. Its lightening qualities might support a more even complexion by removing dark spots.

Acne-prone skin

The anti-inflammatory qualities of vitamin E can be beneficial for skin that is prone to acne. It contributes to a calmer and brighter complexion by lowering acne-related redness and irritation.

In closing

Both vitamins C and E have several advantages for your skin. While Vitamin C encourages collagen production, brightens the skin and lessens the effects of photoaging, Vitamin E offers antioxidant protection, moisturization and wound healing capabilities. 

When selecting the best vitamin for your skin type, consider your age-related problems and any particular skin conditions. A dermatologist’s consultation might offer specialized advice. 

In the end, adding Vitamin E, Vitamin C or both to your skincare regimen will help you attain healthier, more beautiful skin.


Can I take vitamin E and vitamin C together daily?

Yes, it is generally safe to take Vitamin E and Vitamin C together daily. Both vitamins offer unique benefits for the skin and can complement each other’s effects.

Which vitamin whitens skin?

Due to its ability to lighten skin, vitamin C is frequently credited with enhancing skin tone and minimizing the appearance of dark patches and hyperpigmentation. Vitamin C can help create a more even and luminous complexion, even if it may not really “whiten” the skin.

Is vitamin E good for anti aging?

Yes, it works as a strong antioxidant to shield the skin from the damage caused by free radicals, accelerating aging. Vitamin E is a powerful anti-aging component since it also encourages skin hydration, boosts collagen formation, and aids in the reduction of fine lines and wrinkles.

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Photograph: debbalba/Envato
The information included in this article is for informational purposes only. The purpose of this webpage is to promote broad consumer understanding and knowledge of various health topics. It is not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.