Best NMN supplements for longevity to buy in 2024

The NMN supplements market is booming, but how do you know which are the best options for you?

What are NMN supplements?

The search for the elixir of life has obsessed mankind for centuries. Today, much of that search has focused on supplements – a growing range of products that claim to make you feel healthier, more alert and keep you younger for longer.

The key element in many of these is nicotinamide mononucleotide (NMN). The body uses this molecule to generate NAD+ which is key to biological functions such as cellular energy, metabolic health and the immune system. These functions decline as we age, leading to the onset of all sorts of problems including heart disease, cancer and neurological disorders.

Different types of NMN supplements

NMN supplements are gaining traction; according to data from Precision Reports, the global NMN market is expected to grow to $386 million by 2027. New products are appearing on the market by the day, and choosing between them can feel rather tricky, so here are a few products which may help you achieve your healthspan goals.

Wonderfeel® Youngr™ NMN

Best NMN supplements for longevity to buy in 2023

Wonderfeel® is designed to provide a unique solution to aging; based on cutting edge science, Youngr™ NMN is a patented formula developed by Harvard Med entrepreneur and inventor Dr Andrew Salzman, who has over three decades of experience in biomedical drug discovery and development, and it is backed by a recent human clinical trial.

Youngr is formulated with emergent antioxidants and sirtuin activation to ensure a multi-targeted approach to defend and slow down biological aging at the cellular level. It contains both the so-called ‘longevity vitamin’ ergothioneine and the powerful antioxidant resveratrol, as well as vitamin D and hydroxytyrosol, an ingredient found in olive oil that serves a dual longevity purpose as both a neuroprotector and cellular antioxidant defence.

Youngr’s unique formula is designed to be highly bioavailable; because the antioxidants help shield the NMN on its journey through the stomach and into the bloodstream, more of NMN reaches its intended biological destination – your cells. Based on the latest human clinical trial, it is also one of the highest NMN doses on the market, containing 900mg dose in just two capsules, and with an introductory offer of $73 for monthly subscribers, it’s a great-value NMN product.

Youngr is an investment in your cells, and one that pays off across your whole body by restoring skin elasticity and boosting energy levels while also optimising organ health and cognition. It also aims to ensure you can enjoy quicker recovery from rigorous activity or even late nights by improving the quality of your sleep

Shop Wonderfeel® Youngr™ NMN

Lifeforce Peak NMN

Peak NMN™ by Lifeforce is a cutting-edge supplement designed to promote overall health and vitality. This product is targeted towards individuals looking to enhance their well-being and slow down the aging process. Lifeforce, a leading supplements brand known for its commitment to quality and innovation, has formulated Peak NMN to stand out in the crowded health supplement market.

What sets Peak NMN apart are its unique features and benefits. This supplement contains NMN, a precursor to the crucial coenzyme NAD+. Scientific research indicates that NMN can help boost NAD+ levels, supporting DNA repair, epigenetic function, cellular rejuvenation, and overall vitality. Elevated NAD+ levels have been linked to improved metabolism and energy production, and can help to manage everyday physical stress.

Peak NMN is a stand-out brand when it comes to NMN supplementation; it contains a concentrated amount of the most stable, long-lasting form of NMN, packing a potent dosage of 125mg pure NMN per capsule.

Peak NMN contains the added benefits of other powerful longevity molecules, including berberine, spermidine and lithium – it’s a high quality way to invest in your biological future.

For optimal results, take one capsule of Peak NMN daily with a meal. It’s essential to follow the recommended dosage and consult a healthcare professional before use, especially if you have any underlying health conditions. Consistency is key, as the benefits of NMN may become more pronounced over time.

Peak NMN by Lifeforce is a promising supplement for individuals seeking to support their overall health and slow down the aging process. While it comes at a slightly higher price point, the potential benefits and Lifeforce’s dedication to quality make it a worthwhile investment for those prioritizing their well-being, especially in a market crowded with lower grade and impure NMN supplements.

Renew your body from the inside out – shop Lifeforce Peak NMN today

Elysium Signal

Research has shown that NAD+ is central to hundreds of metabolic processes, but this is especially true in the mitochondria, where NAD+ plays a crucial role in the key reactions that take place.

The mitochondria are the powerhouses of the cell, taking glucose and oxygen and converting it into the cellular energy we need to grow, repair and function. However, as we age, mitochondrial function declines, and this means less energy for repair and renewal.

Signal targets metabolic aging by supplying declining metabolites and acting to preserve and help generate new mitochondria.

The renowned aging researcher Leonard Guarente, PhD, is Elysium’s founder and chief scientist; he describes Signal as a novel, mitochondria-centric product that is “formulated to counter aging-dependent declines in metabolism by promoting youthful energetics and metabolic efficiency”.

Aging is a double whammy for our mitochondria; not only do NAD+ levels drop off as we age, but the activity of NAD-dependent enzymes like SIRT3 declines as a result of aging-induced changes in cellular metabolism. SIRT3 helps facilitate key reactions inside the mitochondria, as well as protecting and generating new mitochondria, so this decline is bad news.

Signal’s SIRT3 Metabolic Activation Complex, honokiol and viniferin, are designed to work synergistically with NMN to activate SIRT3 to promote mitochondrial health and synthesis, which in turn support metabolic health.

As well as increasing NAD+ levels by 40% and activating SIRT3, Signal also promotes healthy metabolic aging by maintaining insulin sensitivity (helping to keep blood sugar at a healthy level), supporting vascular heath (critical for athletic endurance) and supporting the process of brown fat thermogenesis – converting sugar and fat into heat to maintain body temperature and help support a healthy metabolism.

Shop for Signal

Elevant NMN-C®

Elevant NMN-C® aims to bring scientific rigour to the supplements market. Elevant, in partnership with the Buck Institute and Seneque Lab, has developed a proprietary form of NMN, called NMN-C®. Using fully synthetic processes, the result is an NMN that is “most likely to be purer and more efficient at raising NAD+ levels” than other NMN products, says Dr Eric Verdin, President of the Buck Institute.

Endorsed by Dr Frank Lipman, a leader in the functional medicine field, Elevant has conducted what it claims to be the first study of its kind to be undertaken on NMN : an OECD toxicology study. The study showed NMN-C® to be an ‘extremely well-tolerated option’ even at highest concentration level (>1500mg/kg/day). NMN-C is used in in-human trials, meaning it meets clinical levels of safety, purity and quality. With 11 clinical trials underway, NMN-C is the most extensive in-human NMN research program to date, and it is the only pharma grade NMN available in the market.

Based on this research, Elevant has developed two products: Prime capsules and Optima chewable tablets. Designed to work together as a daily combination, these complementary delivery forms target different routes of absorption, one aiming for the long-term while the other releases immediate effects:

  • Elevant Prime  Capsules: zero in on cellular repair to decrease risks of metabolic diseases, such as diabetes, or cardiovascular dysfunctions, providing your cells with the fuel they need to operate and combat infections.
  • Elevant Optima Chewable tablets: aid in combatting plunges in energy and focus. Optima enters your body through sub-lingual sensors, allowing NMN-C® to operate faster and promotes brain clarity and enhanced cognition functions.

In an environment in which many suppliers make bold and over-inflated claims about the efficacy of their supplements, Elevant focuses on scientific rigour and analysis and aims to appeal to those who want to see independent recognition of a company’s claims before committing to a purchase.

Shop for Elevant Optima

Shop for Elevant Prime

LIPO NAD+ Complete – Powdered Liposomal NAD+, NMN, & NR

For one of the strongest and fastest acting supplements on the market, look to Liposomal NMN from Renue by Science. This is a powder-based liposomal NMN product which has been shown to be up to six times more bioavailable than liquids. It takes advantage of liposomes – delivery vehicles that transport substances into the body either by facilitating absorption directly in the mouth or by preventing its breakdown by stomach acid. The product comes in 250mg tables and has been FDA inspected and ISO-Certified.

The Liposomal NAD+ Complete Oral Spray is a new product in their line. Ingredients are delivered orally to be absorbed through mucous membranes and absorbed directly into the bloodstream.

As with IV injections, sublingual delivery provides peak serum NMN, NAD+ and NR elevations. In addition to allowing active ingredients to reach alternative tissues, liposomes prolong circulation time in the blood.

Shop for Liposomal NAD+

Shop for Lipo NAD⁺ Complete Oral Spray with NAD⁺, NMN and NR

Making your choice

These are just some of the NMN products available, with a quick search of the market revealing myriad options. The best way to check on quality is to look at the ingredients and ascertain which products have been independently tested and approved. If you find a product which is significantly cheaper than the others, you should consider that there may be a very good reason for that – if it seems too good to be true, it probably is.

Photograph: prathanchorruangsak/Envato
The information included in this article is for informational purposes only. The purpose of this webpage is to promote broad consumer understanding and knowledge of various health topics. It is not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.