What is inflammaging and why is it trending on TikTok?

Inflammaging, a term gaining traction on social media platforms like TikTok, refers to the chronic, low-grade inflammation that occurs with aging.

This phenomenon has garnered attention due to its overall health and longevity implications.

As people age, their immune systems become dysregulated, leading to chronic inflammation. This inflammation is linked to various age-related diseases, including cardiovascular disease, Alzheimer’s disease and cancer [1].

Inflammaging contributes to the decline in physiological function and the onset of age-related ailments.

Researchers believe that inflammaging stems from a combination of genetic predisposition, environmental influences and lifestyle choices.

Factors like obesity, smoking, poor diet and sedentary behavior can exacerbate inflammation, while healthy habits like regular exercise and a balanced diet can help control it.

Studies have shown that inflammaging is associated with changes in the immune system, particularly an increase in pro-inflammatory cytokines and a decrease in anti-inflammatory factors [2]. This imbalance can lead to chronic inflammation that damages tissues and organs over time.

On TikTok, users share information about inflammation and discuss ways to combat it through lifestyle changes, dietary interventions and skincare routines [3].

While some of these discussions may lack scientific rigor, they reflect a growing interest in aging-related topics among younger audiences.

Understanding inflammaging is crucial for developing interventions to promote healthy aging and reduce the burden of age-related diseases. By addressing chronic inflammation early on, individuals can improve their quality of life and extend their lifespan.

[1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146930/
[2] https://www.nature.com/articles/s41392-023-01502-8
[3] https://www.tiktok.com/search?q=inflammaging&t=1707353932030

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