A new type of wearable aims to make sure you’re dressed for longevity success.

Wearables and implantable therapies are fast becoming antiaging must-haves, whether it’s continuous glucose monitoring, tracking recovery times or mapping brain signals. Often these devices respond to information detected in the body, but what if this were a two-way street with a longevity wearable that could read the body’s bioelectric signals and then respond with person-specific preventative and healing therapy? It’s time to suit up!

Longevity.Technology Sponsored Content: Tremendous advances have been made in wearable diagnostic and therapeutic devices in recent years, including developments in diabetes, where blood glucose levels are continuously monitored and insulin is delivered accordingly; the categories of pain, epilepsy, hypertension and electrophysiology have also benefitted from wearable technology. Garments that read bioelectric signals and respond with specific prophylactic or therapeutic treatments represent another significant advancement and BodStim’s approach suits us right down to the ground!

BodStim, a bioelectric bodysuit developed by BioLeonhardt Whole Body, delivers patented and patent-pending bioelectric signals to increase circulating Klotho, a powerful antiaging and muscle regeneration protein [1].

The longevity wearable features electrodes optimally placed over and under the kidneys and over skeletal muscles; this means that rather than fumbling with sticky electrode placement every time, the user simply dons the comfortable stretch suit as the electrodes and cables are integrated into the fabric, all situated in the correct positions.

A small pre-programmed bioelectric stimulator is then plugged into the fitted connector pocket to hold it firmly in place. But the real draw is the science behind the suit – early clinical study results have shown that BodStim technology can increase circulating Klotho levels by 150% over baseline levels.

Klotho has been recognised for over 30 years as a gene involved in the aging process in mammals [2].

Nearly 3,000 published papers have identified that low Klotho levels are associated with accelerated aging conditions, including high blood pressure, calcification of arteries and heart valves, early-onset dementia [3], cancer, arthritis and other aging-related ailments.

New data are emerging indicating that increasing Klotho levels may significantly improve and even reverse aging-related declines in health [4].

These include reducing:

• The risk of chronic inflammation
• Calcification of arteries, heart valves, and brain blood vessels [5]
• The risk of cancer
• The risk of depression, addiction, Alzheimer’s disease and other dementias [6]

In addition, increasing Klotho levels has been shown to improve muscle regeneration and recovery from kidney failure and stroke [7].

The company is also researching the addition of bioelectric stimulation in the longevity wearable for a number of therapeutic benefits through the expression of additional proteins for enhanced muscle building and recovery (Follistatin, IGF1, and LIM Muscle), improved circulation and exercise recovery (VEGF, PDGF) and improved skin and tendon elasticity (tropoelastin).

Furthermore, in conjunction with other Leonhardt’s Launchpads start-ups, the BodStim team is developing bioelectric stimulation signals to improve gut microbiota function to strengthen the immune system, and additional signals to increase serotonin production to improve mood, although these endeavours are still in development and have not yet been proven in human clinical trials to be safe and effective.

Manufactured for Leonhardt Ventures by Wiemspro, BodStim bodysuits were initially developed for use in the Electronic Muscular Stimulation (EMS) training system. EMS delivers low intensity or mid-frequency electrical impulses to muscles during workouts, and this form of training increases muscle mass quickly, effectively and visibly, whether for sporting, therapeutic or aesthetic purposes.

Electrodes are strategically located throughout the bodysuit to produce natural muscle contraction when stimulated, and the impulses reach the deepest layers of muscle, which are more difficult to activate through conventional training. Weimspro bodysuits are commercially available now.

Do you know your age in KlothoYears?

Once you know how vital the Klotho protein is to human health, the next step is to test your Klotho levels. KlothoBios, another Leonhardt’s Launchpads start-up, is dedicated to increasing public awareness about Klotho, offering personal Klotho testing, and helping people improve their Klotho levels with its proprietary technology.

Customers can order an individual test from KlothoYears for $599, or a less immediate but more economical “crowdsourcing” version at $199, which allows the company to group multiple tests to keep costs down. Up to 50% of all profits from test sales will be redirected into Klotho-related research and development, including Klotho-based therapeutics.

Blood is drawn at a clinic or via a home visit. The sample is then returned by mail to the clinical laboratory, where an ELISA (Enzyme-Linked Immunosorbent Assay) test is performed.

Test results are sent to the customer with detailed information about increasing Klotho levels, clinical studies and products that might benefit their health and lifespan. Subsequent tests can monitor the results of Klotho-enhancing lifestyle changes.
Find out more and order a Klotho test and mobile phlebotomy services.

Lionheart Health, direct to consumer and physician initiatives

Later this year, the company is preparing to launch Lionheart Health, a consumer products online store, and Lionheart Health physician sales and service. The product offerings will include portable and in-clinic bioelectric stimulators with organ-specific signals to treat erectile dysfunction, incontinence, hypertension, sleep disorders, hair loss, skin aging, eczema, knee joint pain, and anxiety and depression. Additionally, sales representatives will offer Pulsed Electromagnetic Field (PEMF) stimulators from Pulsed Energy Technologies.

The PEMF process involves generating and directing powerful, pulsed energy waves toward damaged or injured areas of the body, giving cells the energy they need to recharge, thus making it easier for the body to restore its health naturally.

Lionheart Whole Body diagnosis and regeneration

As well as longevity wearables, the long-term vision for BioLeonhardt Whole Body is to develop a whole-body regeneration chamber that scans the entire body, takes and analyses blood samples, completes genetic and polymorphism tests, and creates a personalised bioelectricity map.

Then, after completing the diagnosis phase, a personalised regeneration protocol will be implemented using bioelectric signalling sequences and biologics with the aim of restoring the body to full health.

BodStim, Klothoyears, KlothoBios and BioLeonhart Whole Body are four of the 38+ innovations in Leonhardt’s Launchpads regenerative medicine incubator UCI Cove in Irvine, California, the development accelerator for Leonhardt Ventures, LLC.

All of the start-ups leverage bioelectric and biologics-based therapies for organ regeneration and healing in five product groups: Heart and Cardiovascular, Brain, Cosmetic and Personal Care, Major Organ Regeneration and Cancer.

The Leonhardt team is creating interventions and therapies that enable physicians to help people heal disease and injuries to live longer, healthier lives. The soon-to-launch consumer products portal is part of the vision to empower people with tools to help them take charge of their health and wellbeing.

Led by Howard Leonhardt, inventor of numerous successful multi-patented medical products, including stent-grafts, percutaneous heart valves and electrical stimulation systems, the company has attracted a group of physicians, researchers and business people with a shared vision.

Rather than long-term management of symptoms and suffering, they envision a day when healthcare will allow people to live longer, healthier lives through preventative wellness practices, and when required, regenerating diseased or injured organs and tissues. As Dr Leslie Miller, Chief Medical Officer for Leonhardt Ventures and an internationally renowned cardiologist, transplant surgeon, and expert in regenerative medicine, stated: “It’s why I get up in the morning.”

More information on BodStim and the 35+ other regenerative medicine innovations incubating in Leonhardt’s Launchpads accelerator can be found HERE.