Projects positively reviewed by NIH to be awarded over $3.4m in 2023, with projected total of over $20m through 2027.
Hevolution Foundation, a global non-profit organization that provides grants and early-stage investments to incentivize research and entrepreneurship in healthspan science, has announced the recipients of its grants program, Hevolution Foundation Advancing Geroscience Efforts (HF-AGE).
First announced in October 2022, the program funds research deemed meritorious and praiseworthy by the National Institute on Aging (NIA), one of the institutes of the US National Institutes of Health (NIH).
“HF-AGE was inspired by my time with the NIA, where I saw so many superb grant proposals that were taken through the review process but ultimately not funded, oftentimes simply for lack of resources,” commented Felipe Sierra, PhD, Chief Scientific Officer of Hevolution Foundation. “I could not be more gratified to see the program come to life via these nine projects that so clearly align with our mission and goals.”
The nine grant recipients are:
- Carlos Aguilar, PhD, University of Michigan at Ann Arbor, Michigan
Understanding and engineering the relationship of muscle stem cells with the neuromuscular junction in aging
- Olga Anczukow-Camarda, PhD, The Jackson Laboratory, Farmington, Connecticut
Building a spatial transcriptomics infrastructure for isoform profiling in aging epithelial tissues
- Holly Brown-Borg, PhD and LaDora Thompson, PhD, University of North Dakota, N Dakota
Cellular Mechanisms of Frailty Onset
- Sean Curran, PhD, University of Southern CaliforniaRNA editing mediates age-related responses to mitochondrial dysfunction
- Samuel Joseph Endicott, PhD, University of Michigan at Ann Arbor, Michigan
PTEN as a regulator of chaperone-mediated autophagy, and its effects on the lysosomal targetome
- Vadim Gladyshev, PhD, Brigham and Women’s Hospital, Boston, Massachusetts
Profiling epigenetic age in single cells and in a high-throughput manner
- Cara Green, PhD, University of Wisconsin, Madison, Wisconsin
The Genetic Landscape Determines the Metabolic Response to Dietary Protein
- Changhan Lee, PhD, University of Southern California
Mitochondrial-Encoded Immunity in Aging
- Shouan Zhu, PhD, Ohio University, Athens, Ohio
Role of protein malonylation in osteoarthritis development during aging and obesity
Sierra concluded: “On behalf of the scientific team at Hevolution Foundation, I would like to congratulate these nine outstanding grant recipients. We look forward to continuing to enable their research over the life cycle of this program, and in so doing, helping to move aging biology and geroscience research forward.”