New panel set to aid detection of inflammation and biological stress biomarkers

Metabolon’s new Biological Stress Discovery Panel will provide insights into biological stress pathways and enable personalized solutions.

Metabolon, Inc, a company providing metabolomics solutions that advance wide variety of research, diagnostic, therapeutic development and precision medicine applications, has announced the launch of its new Biological Stress Discovery Panel.

Metabolomics is the large-scale study of all small molecules in a biological system; the only ‘omics technology that provides a complete current-state functional readout of a biological system, metabolomics can help researchers see beyond the genetic variation of individuals, capturing the combined impact of genetic and external factors such as the effect of drugs, diet, lifestyle and the microbiome on human health.​ By measuring thousands of discrete chemical signals that form biological pathways in the body, metabolomics can reveal important biomarkers, enabling a better understanding of a drug’s mechanism of action, pharmacodynamics, and safety profile, as well as individual responses to therapy. ​

Part of its portfolio of metabolomics services, Metabolon’s Biological Stress Discovery Panel encompasses 114 metabolites strongly associated with chronic stress and provides insights into various biological stress pathways, including inflammation, injury, circulation, and oxidative stress. The panel also examines other signaling molecules and signatures that can determine an individual’s capacity to address stress and identify the presence and activity of specific stressors.

Longevity.Technology: Prolonged periods of stress in the human body contribute to the development of numerous diseases. Stressors result from internal and external factors such as injuries, toxic substances, infections, and the necessary disturbances caused by food intake and metabolism – these can all negatively impact our well-being. Intricate coordination between the circulatory, endocrine, nervous and immune systems allows the body to mount an appropriate response to these stressors, but this complex system is poorly understood.

The Biological Stress Discovery Panel incorporates new visualization tools and allows researchers to compare results across different data sets to identify statistically significant changes in metabolite abundance. Researchers also have access to detailed associations between metabolites and biological pathways that can help uncover biological significance.

“Metabolon is at the forefront of research, enabling a better understanding of disease mechanisms,” said Annie Evans, Senior Director of Research and Development at Metabolon.

“Our new Biological Stress Discovery Panel provides an in-depth understanding of the specific biological stressors impacting individuals, thereby enabling the development of tailored solutions to address unique needs and overcome disease management challenges.”

Photograph: WildMediaSK/Envato