New product Insideout aims to tackle the most visible aspects of aging: skin and mobility

Elevant’s new supplement combines pharma grade NMN with European-sourced hyaluronic acid.

Elevant has launched a new addition to the brand’s targeted approach of slowing down aging at a cellular level.

Combining pharmaceutical grade NMN with European-sourced hyaluronic acid, Elevant’s new product, Insideout, aims to tackle both skin and mobility – two of the most visible aspects of aging.

Longevity.Technology: Elevant burst onto the longevity supplement market in 2021 with two products, PRIME and OPTIMA. The company sought to differentiate itself from its competition by elevating its products above run-of-the-mill NMN supplements, and to do this, it went back to the science, partnering with the world-renowned Buck Institute for Research on Aging to develop a unique proprietary form of NMN, called NMN-C®, which has been shown to be purer and more efficient.

Elevant is the sole brand to have fully-integrated manufacturing process in Europe from formulation to final product, and the company strives to bring scientific rigour and pharma grade standards to the supplements market.

Insideout is Elevant’s latest product innovation; launched in the US market in December 2022, Insideout is a novel combination of NAD+ boosting NMN-C and hyaluronic acid. While NMN is well-documented as a longevity supplement, hyaluronic acid more often found as an ingredient in skin care products; however, hyaluronic acid can prove to be a game-changer for joint care.

Hyaluronic acid is a naturally occurring polysaccharide found in the body. Present in high concentrations in the skin hyaluronic acid plays a role in retaining moisture and “plumping” the skin, giving it a more youthful appearance (which is why it is a darling of the skincare world). However, it is also present in the joints, acting as a lubricant and shock absorber in joints, and can also play a role in wound healing and tissue repair.

More than 50% of the body’s total content of hyaluronic acid is located within the skin and synovial fluid, a thick fluid that lubricates, cushions and reduces friction between joints.

Hyaluronic acid can help to reduce the appearance of fine lines and wrinkles, and improve skin elasticity, as well as alleviate joint pain and improve mobility, but as we age, our body’s production of hyaluronic acid decreases, leading to drier and less plump skin and joint problems. Using products that contain hyaluronic acid can help to supplement the skin and joints’ natural levels and improve their overall appearance and function.

How does Insideout work?

Insideout aims to nourish cells from the inside so they look and feel younger on the outside.

Its combination of ingredients mean that hyaluronic acid can help maintain a supple, plump and well-moisturised skin and help joints move smoothly, while NMN-C boosts NAD+ levels. Research has shown that NAD+ is responsible for 90% of cellular energy including system repair, protection and renewal. NAD+ allows skin cells to proliferate healthily to prevent signs of skin deterioration and protects joints from inflammatory reactions by maintaining cellular metabolic health.

As we age, both hyaluronic acid and NAD+ levels within the body decrease, accelerated by external factors such as UV-exposure or air pollutants. It leads to dryness, reduction of skin elasticity and eventually appearance of wrinkles and fine lines at skin level. Joint-wise, less lubrication and protection lead to inflammation and joint pain.

This is where Insideout comes into the picture, with a double action for intensified and lasting results:

  • Insideout acts as a sponge and a shield within skin cells; while hyaluronic acid holds onto water to maintain skin moisture [1], NMN-C restores NAD+ levels to reinforce cell protection from UV damage [2]. The upshot is that skin should look and feel healthier.
  • Insideout acts as a lubricant and healer around joints; hyaluronic acid lubricates connective tissues and cartilage [3] while NMN-C® reinforces bone tissue stem cells [4] and boosts NAD+ to activate anti-inflammatory properties [5]. Joint lubrication is progressively restored, and joint pain reduced.

One pouch of Insideout contains 120 capsules, with the recommended dosage being two capsules per day. The resealable and isothermal pouch gives optimum product conservation and convenience of use. Elevant recommends 60 days of supplementation to confer long-term benefits.

As Dr Frank Lipman, leader in function medicine, told us: “I’ve seen the research, I’ve used it myself, I believe in this particular product so that is why I am using NMN-C.”

Eric Verdin, President of the Buck Institute, says: “What really differentiates NMN-C, is the fact that it is fully synthetic, whereas other NMN products on the market actually are using enzymatic products, from bacteria, for the last step of the synthesis. So this fully synthetic product actually is likely to be a pure and more efficient at raising NAD+ levels [6].”

READ MORE: Back to biology – Eric Verdin talks NMN and longevity supplements