New partnership brings early cognitive screening into everyday wellness, bringing brain health closer to prevention and longevity.
Most people do not think about brain health until something feels off. A forgotten name. A missed appointment. A moment of mental fog that lingers just a little too long. That is the pattern that the app-based brain health test PREMAZ is trying to disrupt.
The Cambridge, UK-backed digital cognitive assessment has partnered with Health is One, a UK-based well-being organization, to expand access to early brain health screening through integrated well-being services. It reflects the slow but meaningful migration of cognitive screening out of specialist or clinical settings and into the kinds of services people already use to stay well.
In brain health, as in longevity more broadly, the most valuable intervention is often the one that happens before decline becomes obvious.
PREMAZ, which was developed by Zest Science in partnership with the University of Cambridge, has worked with other clinics before, but this collaboration stands out because it is the first to focus on weaving early cognitive testing into everyday wellness.
Health is One provides evidence-based support across counselling, neurodiversity services, brain health programs and lifestyle interventions aimed at improving long-term well-being. Through the partnership, PREMAZ will be introduced into the organization’s brain health and cognitive well-being services, giving clients access to a 10–15-minute digital assessment designed to detect subtle changes in memory function.
For years, brain health has largely been treated like an emergency category: something to investigate when symptoms become disruptive enough to raise alarms. This partnership suggests a different model – one where checking in on cognitive health becomes more like monitoring sleep, stress or cardiovascular risk: a regular part of maintaining long-term function.
How PREMAZ works
Traditional cognitive tests tend to ask a fairly simple question: did you remember something correctly, or not? PREMAZ tries to look deeper. Instead of only measuring whether a memory is present, it measures how precisely that memory is stored and recalled – what the company calls “memory precision”.
Think of it this way: it is one thing to remember that you left your keys somewhere in the house. It is another thing to remember they are on the kitchen counter, beside the fruit bowl, under yesterday’s mail.
That difference in detail may seem small, but it can be important. In neurodegenerative diseases such as dementia, memory does not always disappear all at once. Often, the edges blur first. The memory is still there, but less sharp. Less exact. Less reliable. That is the insight PREMAZ is built around.
Developed by medical doctor Julia Cooney in collaboration with researchers from the Cambridge University Memory Lab, the platform is designed to capture these early, subtle shifts in memory quality that traditional assessments may miss. In simpler terms, it is trying to spot the first faint cracks rather than wait for the wall to collapse. And in prevention, that earlier window is everything.
A partnership built for the real world
Health is One’s integrated approach spans mental health support, sleep optimization, stress management and lifestyle interventions – the very kinds of factors that increasingly shape how the longevity world talks about cognitive aging. That makes the partnership more than a deployment. It creates a real-world environment where early cognitive signals can be observed alongside the daily habits and pressures that may influence long-term brain health.
Dr Julia Cooney, founder and CEO of Prema Cognition (PREMAZ), said that brain health is emerging as a critical healthcare challenge, and she explained that by partnering with Health is One, the company is able to integrate advanced cognitive screening into practical, real-world well-being services, where it can provide an immediate impact.
“Our goal with PREMAZ is to make sensitive cognitive assessment accessible earlier, before significant decline occurs, so individuals and clinicians can take meaningful preventative action,” she said.
Kevin McGeever, the Director at Health is One, explained that by integrating PREMAZ into their services, they can provide clients with a powerful new tool to help them understand their brain health and take proactive measures to maintain their cognitive well-being.
The bigger research and longevity angle
The partnership also feeds into PREMAZ’s broader research collaboration with the University of Cambridge’s Memory Lab, which is focused on understanding how lifestyle factors may influence long-term dementia risk.
For years, the sector has argued that aging is not just about treating disease later; it is about identifying risk earlier and building systems that help people stay functional for longer. However, brain health has often lagged behind that ambition, in part because subtle cognitive decline is hard to measure before symptoms become visible.
PREMAZ is positioning itself as one answer to that problem. By combining a sensitive digital cognitive assessment with data from real-world well-being programs, the partnership may help generate more useful insights into how sleep, stress, mental health and other everyday behaviours shape cognitive function over time. That does not mean a 10-minute test suddenly solves dementia; it does mean the field may be inching closer to something more practical: a way to connect early warning signs with actionable changes before the damage becomes harder to reverse.
That is the more progressive reading of this announcement. Not that technology alone will save brain health, but that better tools, used earlier and in the right settings, can make prevention less abstract.
PREMAZ is already expanding across healthcare providers, research institutions and brain health programs in the UK and the US. But this latest partnership may be one of its clearest signals yet about where preventive medicine is going.
If the future of longevity is about extending the quality of those added years, then brain health cannot remain a late-stage conversation. This is what makes the PREMAZ-Health is One deal worth watching. It moves early cognitive screening out of the realm of specialist intervention and closer to ordinary care, where prevention actually has a chance to work.
