What everyone ought to know about NMN

There is a whole raft of information about longevity supplements out there, but NMN is one supplement that warrants a closer look. Check out our NMN FAQ and start your longevity journey ASAP.

Nicotinamide adenine dinucleotide, or NAD+, is a critical coenzyme. Found in every cell in the body, NAD+ plays a role in myriad metabolic processes, including converting sugar into energy (respiration), helping proteins regulate cellular functions and keeping our DNA healthy. Low levels of NAD+ are associated with accelerated aging and increased risk of heart disease, Alzheimer’s disease and type 2 diabetes.

Longevity.Technology: NAD+ levels decline with age, partly because we produce less as we get older and partly because we use it up at a faster rate as our bodies are incurring more damage and under increased stress. Keeping NAD high should, in theory, keep us younger and fitter for longer, and this means that NAD+ boosters – supplements that can help increase your NAD levels – are becoming increasingly popular. One such booster is nicotinamide mononucleotide (NMN) a precursor of NAD+, which means it is part of the reaction that generates NAD+; in fact, NMN could almost stand for Need More NAD+!

 

NMN is crucial to the search for NAD+ because the latter is not very bioavailable. Ingesting it directly in supplement form is difficult, which is why scientists have turned their attention to other molecules such as NMN. Once inside the body, NMN can be used to build NAD+ via a chemical reaction, so supplement with NMN – so the theory goes – and you will increase your levels of NAD+.

The expert’s view

As the scientific community delves deeper into the mechanisms of aging, NAD+ has emerged as a pivotal molecule in the conversation around longevity. 

AVEA Life’s Vitality Bundle has captured the attention of health experts for its targeted approach to increasing NAD+ levels, a key factor in cellular health.

James Raaff, an Integrative Health Practitioner, directly addresses the product’s impact: “Avea’s Vitality Bundle presents an effective way for my clients to increase intracellular NAD+ levels safely. This little miracle essentially prevents cellular ageing.”

In tandem with Raaff’s observation, Simone Singery, a Registered Dietitian, points out the broader environmental challenges our cells face and the protective role of NMN: “Modern lifestyles expose us to numerous sources of damage; from poor diet to lifestyle. NMN is the most effective supplement I have prescribed to protect against this damage.”

These testimonials from health professionals highlight the Vitality Bundle’s capacity to support cellular longevity and defend against the daily wear and tear inflicted by our environment and lifestyle choices. 

Through the lens of expert experience, AVEA Life’s formulation is presented not just as a nutritional supplement, but as a fundamental part of a comprehensive health and longevity strategy.

Researching NMN

Research into the benefits of NMN have ramped up, with studies in mice demonstrating increases in life span [1], improved muscle endurance and improved heart, liver and kidney health; a slowdown in the progression of Alzheimer’s and protection against diabetes complications, were also observed.

Multiple studies show that NMN can raise NAD levels. A study in Nature Magazine showed that oral supplementation of NMN was well tolerated by the body and led to increased levels of NAD in middle aged and older adults [2]. There is also evidence of direct biological benefits. Studies have also shown that it has positive impacts on conditions ranging from diabetes to Alzheimer’s and ischemia [3] and have demonstrated that NAD+ levels play a key role in regulating inflammation and cell survival during both immune response and aging.

What everyone ought to know about NMN

Can NAD+ slow aging?

There is plenty of evidence about the effectiveness of NAD in the fight against aging. Studies show that it can increase longevity within mice [1] and boost mitochondria which are the cell’s energy factories [4]. It works as a carrier electron moving one to the other and helping cells to do their job. We literally can’t function without it, which is why, as levels decline with age, we become more susceptible to certain conditions.

While it is possible to boost NAD+ levels and slow this decline with a healthy exercise and dietary regime, there is now a more direct approach available. The AVEA Life Vitality Bundle represents the latest in longevity science, offering a strategic blend of ingredients that enhance physical and mental performance. This product not only supports sustained energy throughout the day but also promotes healthy cellular aging, addressing the biological processes that contribute to aging.

With the AVEA Life Vitality Bundle, maintaining youthful vigor and resilience is more accessible. It stands as an essential ally, providing a simple yet effective daily boost that is poised to support the body’s innate energy reserves and combat the passage of time. By supporting the intricate cellular functions that combat aging, the AVEA Life Vitality Bundle offers a proactive pathway to wellness and longevity, making it a significant addition to the NAD+ boosting regimen.

How do NMN supplements work?

Taking an NAD+ precursor, rather than going for straight NAD+ supplements makes sense because NAD+ cannot easily enter the body because of the barrier of the cell membrane. However, NMN doesn’t have this problem, as it’s a smaller molecule and can take advantage of molecular transporter to be absorbed into cells. Once inside the cell, NMN can be changed into NAD+ and get to work.

Is NMN safe?

Although research is ongoing, there is no reason to believe NMN has any safety issues in high doses. It is a safe and effective way to boost NAD levels in your body, thereby promoting all sorts of healthy knock-on benefits. As clinical studies continue scientists are learning more about how it works all the time.

Takeaway

As we continue to explore the benefits of NAD+ and its impact on longevity, the Vitality Bundle offers a proactive approach to maintaining health and vitality through the years. It represents a commitment to oneself, a daily step towards a future of sustained wellness. The promise of the AVEA Life’s product is clear: it’s a practical tool in the ongoing effort to maintain the vibrancy of youth and the health of age.


[1] https://pubmed.ncbi.nlm.nih.gov/27127236/
[2] https://www.nature.com/articles/s41467-018-03421-7
[3] https://jbiomedsci.biomedcentral.com/articles/10.1186/s12929-019-0527-8
[4] https://pubmed.ncbi.nlm.nih.gov/24360282/

Images courtesy of Eduardo Madrid / Unsplash and Nutriop